Síndrome Nefrótico

“De la teoría al manejo”

  • Gustavo Carvajal-Barrios Universidad el Bosque. Subred Integrada de Servicios de Salud Norte, E.S.E. Secretaría Distrital de Salud de Bogotá y del Centro Médico Colsubsidio Suba. Bogotá, Colombia. https://orcid.org/0000-0002-4093-8103
  • Natalia Mejía Facultad de Medicina, Universidad de los Andes. Hospital Universitario Fundación Santa Fe de Bogotá. Bogotá, Colombia.
  • Luz Estella González Ch Universidad el Bosque. Universidad del Rosario. Universidad de la Sabana. Fundación Cardioinfantil-Instituto de Cardiología. Bogotá, Colombia.
  • Adriana Florez Hospital Universitario. Fundación Santa Fe de Bogotá. Bogotá, Colombia.
  • Carlos M. Restrepo CIGGUR. Escuela de Medicina y Ciencias de la Salud, Universidad del Rosario. Bogotá, Colombia.
  • Ricardo Gastelbondo Universidad el Bosque. Departamento de Nefrología Pediátrica, Fundación Cardioinfantil-Instituto de Cardiología. Bogotá, Colombia.
Palabras clave: Edema, glomerulopatía, glucocorticoide, hiperlipidemia, hipoalbuminemia, podocitos, proteinuria

Resumen

El síndrome nefrótico (SN) es la manifestación más frecuente de las glomerulopatías primarias no inflamatorias en niños y se caracteriza proteinuria masiva con hipoalbuminemia profunda, con hiperlipidemia y edema secundarios.El SN de etiología primaria entre 15 al 30% de causa de enfermedad renal crónica terminal (ERCT) en Colombia. Dadas las diferencias en el tratamiento instaurado entre pediatras y nefrólogos pediatras, en las dosis y la duración  del primer tratamiento, la presencia de  efectos adversos asociados a la inmunosupresión, así como los resultados finales, según el centro médico y el recurso humano disponible, se ha realizado esta revisión en un intento de ampliar el conocimiento de la enfermedad, unificando los avances genéticos que han caracterizado el pronóstico así como las nuevas opciones terapéuticas en el manejo de los pacientes difíciles.

 

 

 

 

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Publicado
2020-02-27
Cómo citar
Carvajal-Barrios, G., Mejía, N., González Ch, L. E., Florez, A., Restrepo, C. M., & Gastelbondo, R. (2020). Síndrome Nefrótico: “De la teoría al manejo”. Pediatría, 52(3), 94-107. https://doi.org/10.14295/p.v52i3.137
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Artículos de Revisión