Infantile hemangioma of the parotid gland. Contribution of two new cases
Article Sidebar
Main Article Content
Abstract
Background: infantile hemangiomas are the most frequent benign vascular tumors in childhood, their most common location being the head and neck, representing 50 % of the masses that affect the parotid gland. Due to the rapid expansive growth of these lesions, significant complications can appear, such as loss of organ function or permanent disfigurement, so early therapeutic intervention is of great importance to minimize these undesirable effects. Case report: We present two cases of patients with parotid hemangioma treated with propranolol, with very favorable results and few or no adverse reactions. Conclusions: Currently, oral propranolol is considered the drug of first choice for treating parotid hemangiomas, showing a good safety profile and excellent efficacy.
Downloads
Article Details
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Creative Commons
License Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)
You are free to:
Share - copy and redistribute the material in any medium or format.
Adapt - remix, transform, and build upon the material The licensor cannot revoke these freedoms as long as you follow the license terms.
• Attribution — You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
• NonCommercial — You may not use the material for commercial purposes.
• ShareAlike — If you remix, transform, or build upon the material, you must distribute your contributions under the same license as the original.
• No additional restrictions — You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.
References
Castañeda Hernández S, De la Cruz Durán H, García López IE, Pérez Morales ME, Sánchez Palacio JL. Uso de propranolol en el tratamiento clínico de hemangiomas infantiles. Revisión sistemática. Revista de la OFIL. 2016; 26(4): 322-29.
Baselga E, Bernabéu J, van Esso Arbolave DL, Febrer MI, Carrasco A, De Lucas R, et al. Consenso español sobre el hemangioma infantil. An Pediatría. 2016; 85(5): 256-65. DOI: https://doi.org/10.1016/j.anpedi.2015.10.004
Wang L, Li S, Gao Q, Lv R, Xu G, li X, et al. Oral propranolol therapy in parotid hemangiomas: A retrospective comparison with other infantile hemangiomas. Head Neck. 2021; 43(5):1553-62. DOI: https://doi.org/10.1002/hed.26625
Romo E, Torreira T, Lara VL, Fernández M, Cárdenas MM. Presentación de 3 casos de hemangiomas infantiles tratados con propranolol. Rev Cuba Pediatría. 2011; 83(3):316-22.
Sifre M, Oltra M, López JV, Albors AM, Sequí JM. Hemangioma parotídeo neonatal: Diagnóstico por resonancia magnética. Acta Pediatr Esp. 2012; 70(6): 262-263.
Gonçalves V, Almeida R. Hemangioma parotídeo tratado con propranolol: A propósito de un caso. Acta Pediatr Esp. 2015; 73(11): 323-9.
Darrow DH, Greene AK, Mancini AJ, Nopper AJ. Diagnosis and management of infantile hemangioma: Executive summary. Pediatrics. 2015; 136(4): 786-91. DOI: https://doi.org/10.1542/peds.2015-2482
Inarejos EJ, Navallas M, Tolend M, Suñol M, Rubio J, Albert A, et al. Imaging evaluation of pediatric parotid gland abnormalities. RadioGraphics. 2018; 38(5):1552-75. DOI: https://doi.org/10.1148/rg.2018170011
Lennon P, Silvera VM, Perez-Atayde A, Cunningham MJ, Rahbar R. Disorders and tumors of the salivary glands in children. Otolaryngol Clin North Am. 2015; 48(1): 153-73. DOI: https://doi.org/10.1016/j.otc.2014.09.011
Oesterreich R, Udaquiola J, Lobos P, Moldes J, Liberto D. Diagnóstico y tratamiento de los tumores de la región parotídea en Pediatría: Cohorte. Cir Pediatric. 2016; 29: 135-41.
Harris J, Phillips JD. Evaluating the clinical outcomes of parotid hemangiomas in the pediatric patient population. Ear Nose Throat J. 2019; 100 (5): 242-45. DOI: https://doi.org/10.1177/0145561319877760
Chen Z-Y, Wang Q-N, Zhu Y-H, Zhou L-Y, xu T, He Z-Y. Progress in the treatment of infantile hemangioma. Ann Transl Med. 2019; 7(22): 692. DOI: https://doi.org/10.21037/atm.2019.10.47
Calderón-Castrat X, Velásquez F, Castro R, Ballona R. Atenolol oral en el manejo del hemangioma infantil: Serie de casos de 46 pacientes. Actas Dermo-Sifiliográficas. 2020; 111(1): 59-62. DOI: https://doi.org/10.1016/j.ad.2019.03.015