Acute lobar nephronia in the pediatric patient. Case report

Main Article Content

Viviana Barragan Arévalo
Juliana Mancera Morales
Viviana Echeverri Restrepo
Jesús Niño Salcedo
Juan Pablo Luengas Monroy

Abstract

Background: Acute focal nephritis is a renal inflammation of bacterial origin, without liquefaction, that affects one or more renal lobes. This entity is underdiagnosed, and few cases are described in the literature. Its recognition is essential due to its relationship with urosepsis and renal scars. It can simulate a kidney tumor. It is associated with malformations of the urinary tract. Diagnostic images are of great value, with ultrasound and tomography being the images of choice. Treatment consists of antibiotic therapy, with generally good evolution. Case report: Male patient, six years old, with two weeks of daily fever, without other symptoms. Regular physical exam. Complete blood count with leukocytosis and neutrophilia. The abdominal ultrasound showed a non-specific renal lesion in the upper left pole. Contrast-enhanced abdominal tomography showed a heterogeneous left renal tumor with poorly defined borders, compromising the renal cortex, capsule, and perirenal space, without calcifications, collections, and evident tumor characteristics, without enhancement with contrast medium. MRI of the abdomen contrasted with a lesion compatible with an inflammatory process. Management with amikacin, cephalothin, and clindamycin for three weeks, with good evolution. Control images with a decreased lesion. Conclusion: Acute focal nephritis is a rare entity in pediatrics. Its recognition is essential due to its impact on renal function. The images of choice are ultrasound and CT. Antibiotic management is recommended for three weeks, the study of associated urinary malformations, ultrasound follow-up, and DMSA scintigraphy to evaluate scars.

Downloads

Download data is not yet available.

Article Details

How to Cite
Barragan Arévalo, V., Mancera Morales, J., Echeverri Restrepo, V., Niño Salcedo, J., & Luengas Monroy, J. P. (2023). Acute lobar nephronia in the pediatric patient. Case report. Pediatría, 55(Suplemento 2), 3–6. https://doi.org/10.14295/rp.v55iSuplemento2.259
Section
Case report

References

Rosenfiled A, Gilckman M, Taylor K, Crade M, Hodson J. Acute focal bacterial nephritis (acute lobar nephronia). Radiology. 1979; 132(1):553-61. DOI: https://doi.org/10.1148/132.3.553

Vergara-Espitia A, Gallo-Urina K, Landinez-Millán G, Camacho-Moreno G, Lozano-Triana C. Nefronía lobar aguda en un niño: reporte de caso. Rev. Fac. Med. 2015; 63(2):321-4. DOI: https://doi.org/10.15446/revfacmed.v63n2.47501

Vijayakumar M, Prahlad N, Nandhini G, Prasad N, Muralinath S. Child with acute lobar nephronia. Indian J Nephrol. 2010; 20(3):162-5. DOI: https://doi.org/10.4103/0971-4065.70847

Cheng C, Tsau Y, Chang C, Chang Y, Kuo C, Tsai I, et al. Acute lobar nephronia is associated with a high incidence of renal scarring in childhood urinary tract infections. Pediatr Infect Dis J. 2010; 29(7):624-8. DOI: https://doi.org/10.1097/INF.0b013e3181d8631a

Piñera C, Loyola F, Hernández P. Nephronia in pediatrics: part of the spectrum of upper urinary tract infections. Clinical cases and review of the literature. Rev Chilena Infectol. 2015; 32(5):564-8. DOI: https://doi.org/10.4067/S0716-10182015000600011

Cano F, Strodthoff P, Muñoz O. Nefritis Aguda Focal. Caso Clínico. Rev. chil. pediatr. 2010; 81(3):247-252. DOI: https://doi.org/10.4067/S0370-41062010000300008

Klar A, Hurvitz H, Berkun Y, Nadjari M, Blinder G, Israeli T, et al. Focal bacterial nephritis (lobar nephronia) in children. J Pediatr. 1996; 128(6):850-3. DOI: https://doi.org/10.1016/S0022-3476(96)70340-2

Granados A, Espino M, Gancedo A, Albillos J, Álvarez-Cortinas J, Molina C. Nefronía focal aguda bacteriana: diagnóstico, tratamiento y evolución. An Pediatr (Barc). 2007; 66(1):84-6. DOI: https://doi.org/10.1157/13097366

Cheng C, Tsau Y, Lin T. Effective Duration of Antimicrobial Therapy for the Treatment of Acute Lobar Nephronia. Pediatrics. 2006; 117(1):84-9. DOI: https://doi.org/10.1542/peds.2005-0917

Similar Articles

1 2 3 4 5 6 7 8 9 10 > >> 

You may also start an advanced similarity search for this article.