Sociodemographic and clinical characterization of pediatric patients with SARS-CoV-2 infection, Subred Sur Occidente, Bogotá, D.C.
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Abstract
Background: SARS-CoV-2 infection is a current public health issue that is becoming important given the possibility of affecting the pediatric population, the limited evidence of the disease in children, and the importance of community viral transmission. Objective: to identify the sociodemographic and clinical characteristics of pediatric patients who developed COVID-19 disease. Methods: A descriptive observational case series study included 181 pediatric patients with a positive RT-PCR test for SARS-CoV-2 infection in the Southwest Subnetwork of Bogotá, D.C., (Colombia). Results: COVID-19 disease in pediatrics presented no significant difference between the sexes. The familial epidemiological link was assessed. Clinical presentation was characterized by tachycardia, tachypnea, and hypotension. Lab test results showed lymphopenia and neutrophilia. Radiological imaging findings are nonspecific, generally involving the lower right and upper left lobes. Fifty-five percent presented uncomplicated disease. Possible at-risk infants were preschoolers, low socioeconomic strata, and children with comorbidities. Forty-two percent required hospitalization, with an average hospital stay of 5.32 days, and 4.41 % hospitalization in the ICU, with a case fatality rate of 1.65 %. Conclusions: SARS-CoV-2 infection in children tends to have a milder course and a good prognosis than in adults, whose impact ranges from clinical (uncomplicated) to social characteristics. The available evidence is scarce and restricts the drawing of conclusions. Therefore, it is recognized that this study fulfills its objective of being a pillar for future research.
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References
Tezer H, Bedir Demirdağ T. Novel coronavirus disease (COVID-19) in children. Turk J Med Sci. 2020; 50(SI-1):592-603. DOI: https://doi.org/10.3906/sag-2004-174
Dong E, Du H, Gardner L. An interactive web-based dashboard to track COVID-19 in real time. Lancet Infect Dis. 2020 May;20(5):533-534. doi: 10.1016/S1473-3099(20)30120-1. Epub 2020 Feb 19. Erratum in: Lancet Infect Dis. 2020 Sep;20(9):e215. DOI: https://doi.org/10.1016/S1473-3099(20)30120-1
Instituto Nacional de salud, Sistema Nacional de Vigilancia en Salud Pública-Sivigila. COVID-19 en Colombia, reporte 03-09-2022. https://www.ins.gov.co/Noticias/paginas/coronavirus.aspx (Fecha de consulta: 03 de septiembre, 2022).
Instituto Nacional de salud, Sistema Nacional de Vigilancia en Salud Pública-Sivigila. COVID-19 en Colombia, reporte 25-10-2021. https://www.ins.gov.co/Noticias/paginas/coronavirus.aspx (Fecha de consulta: 25 de octubre, 2021).
Shandera, W, Clark, E. Common viral respiratory infections. En Papadakis MA, McPhee SJ, Rabow MW, editores. Current Medical Diagnosis and Treatment. 2020. McGraw-Hill.
Licari A, Votto M, Brambilla I, Castagnoli R, Piccotti E, Olcese R, Tosca MA, Ciprandi G, Marseglia GL. Allergy and asthma in children and adolescents during the COVID outbreak: What we know and how we could prevent allergy and asthma flares. Allergy. 2020; 75(9):2402-2405. DOI: https://doi.org/10.1111/all.14369
Alsohime F, Temsah MH, Al-Nemri AM, Somily AM, Al-Subaie S. COVID-19 infection prevalence in pediatric population: Etiology, clinical presentation, and outcome. J Infect Public Health. 2020 Dec;13(12):1791-1796. DOI: https://doi.org/10.1016/j.jiph.2020.10.008
Mehta NS, Mytton OT, Mullins EWS, Fowler TA, Falconer CL, Murphy OB, Langenberg C, Jayatunga WJP, Eddy DH, Nguyen-Van-Tam JS. SARS-CoV-2 (COVID-19): What Do We Know About Children? A Systematic Review. Clin Infect Dis. 2020 Dec 3;71(9):2469-2479. DOI: https://doi.org/10.1093/cid/ciaa556
Comisión Económica para América Latina y el Caribe (CEPAL), Los impactos sociodemográficos de la pandemia de COVID-19 en América Latina y el Caribe (LC/CRPD.4/3), Santiago, 2022.
Qiu H, Wu J, Hong L, Luo Y, Song Q, Chen D. Clinical and epidemiological features of 36 children with coronavirus disease 2019 (COVID-19) in Zhejiang, China: an observational cohort study. Lancet Infect Dis [Internet]. 2020; 20(6):689-96. DOI: https://doi.org/10.1016/S1473-3099(20)30198-5
Posfay-Barbe KM, Wagner N, Gauthey M, Moussaoui D, Loevy N, Diana A, L'Huillier AG. COVID-19 in Children and the Dynamics of Infection in Families. Pediatrics. 2020; 146(2):e20201576. DOI: https://doi.org/10.1542/peds.2020-1576
Riedel S, Hobden JA, Miller S, Morse SA, Mietzner TA, Detrick B, Mitchell TG, Sakanari JA, Hotez P, Mejia R. Coronaviruses. En: Jawetz M y Adelberg’s Medical Microbiology, 28e. 2019. McGraw-Hill.
Sperotto F, Friedman KG, Son MBF, VanderPluym CJ, Newburger JW, Dionne A. Cardiac manifestations in SARS-CoV-2-associated multisystem inflammatory syndrome in children: a comprehensive review and proposed clinical approach. Eur J Pediatr. 2021 Feb;180(2):307-322. DOI: https://doi.org/10.1007/s00431-020-03766-6
Bhuiyan MU, Stiboy E, Hassan MZ, Chan M, Islam MS, Haider N, Jaffe A, Homaira N. Epidemiology of COVID-19 infection in young children under five years: A systematic review and meta-analysis. Vaccine. 2021 Jan 22; 39(4):667-677. DOI: https://doi.org/10.1016/j.vaccine.2020.11.078
Bong CL, Brasher C, Chikumba E, McDougall R, Mellin-Olsen J, Enright A. The COVID-19 Pandemic: Effects on Low- and Middle-Income Countries. Anesth Analg. 2020; 131(1):86-92. DOI: https://doi.org/10.1213/ANE.0000000000004846
Escosa-García L, Aguilera-Alonso D, Calvo C, Mellado MJ, Baquero-Artigao F. Ten key points about COVID-19 in children: The shadows on the wall. Pediatr Pulmonol. 2020; 55(10):2576-2586. doi: 10.1002/ppul.25025. Epub 2020 Aug 22. PMID: 32790245; PMCID: PMC7436376. DOI: https://doi.org/10.1002/ppul.25025
Yasuhara J, Kuno T, Takagi H, Sumitomo N. Clinical characteristics of COVID-19 in children: A systematic review. Pediatr Pulmonol. 2020; 55(10):2565-2575. DOI: https://doi.org/10.1002/ppul.24991
Ministerio de Salud y Protección Social. Manual de lineamientos base para la formulación de definiciones de caso en vigilancia en salud pública. Aplicación en COVID-19. Octubre 2020. Bogotá, Colombia.
Parri, N; Lenge, M; Buonsenso, D. Coronavirus Infection in Pediatric Emergency Departments (CONFIDENCE) Research Group (2020). Children with Covid-19 in Pediatric Emergency Departments in Italy. The New England journal of medicine, 383(2), 187–190. DOI: https://doi.org/10.1056/NEJMc2007617
Villegas, J; Villegas, O; Villegas V. Semiología de los signos vitales: Una mirada novedosa a un problema vigente. Revisión de tema. 2012. Volumen 12 Nº 2. pp 221-240. DOI: https://doi.org/10.30554/archmed.12.2.10.2012
Celkan TT. What does a hemogram say to us? Turk Pediatri Ars. 2020 Jun 19;55(2):103-116.
Karadag-Oncel E, Ozsurekci Y, Kara A, Karahan S, Cengiz AB, Ceyhan M. The value of mean platelet volume in the determination of community acquired pneumonia in children. Ital J Pediatr. 2013; 8:39:16 DOI: https://doi.org/10.1186/1824-7288-39-16
Saavedra C. Consenso colombiano de atención, diagnóstico y manejo de la infección por SARS CoV-2 en establecimientos de salud. Recomendaciones basadas en consenso de expertos e informadas en la evidencia (resumen ejecutivo). Infectio. 2020; 24(3) supl. 1:1-153. DOI: https://doi.org/10.22354/in.v24i3.851