Grave´s disease in a male adolescente, case report and literature review

Main Article Content

Juan Sebastián Afanador Ardila
Julián Eduardo Jaimes Salazar
Nelson Muñoz Álvarez

Abstract

Background: Hyperthyroidism is uncommon in the pediatric population, representing only 1-5 % of all hyperthyroidism diagnoses in the general population. However, 84-99 % of these cases are attributed to Graves' disease, with a peak incidence in adolescence and a higher prevalence in females (3:1 - 5:1). Despite its low incidence, Graves' disease is the most common cause of hyperthyroidism in childhood, characterized by autoimmune stimulation of thyroid-stimulating hormone receptors (TRAb), clinically presenting with goiter, hyperthyroidism, and infiltrative ophthalmopathy. Diagnosis is established by suppressing thyroid-stimulating hormone (TSH) levels, associated with the presence of antibodies against the TSH receptor (TRAb). Case Report:


In this document, we present the case of a male adolescent diagnosed and successfully managed with Graves' disease. Additionally, we provide a literature review on this condition with low pediatric incidence. Conclusions: The literature review emphasizes the need for early detection and proper management of this condition to prevent long-term complications. This case highlights the complexity of thyroid disorders in adolescence and the importance of an interdisciplinary approach for its management.

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How to Cite
Afanador Ardila, J. S., Jaimes Salazar, J. E., & Muñoz Álvarez, N. (2024). Grave´s disease in a male adolescente, case report and literature review. Pediatría, 56(Suplemento 1), e452. https://doi.org/10.14295/rp.v56iSuplemento 1.452
Section
Case report

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