Opsoclonus-myoclonus syndrome associated with persistent diarrheal disease: Case report in a male infant

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Paula Andrea López Vergara
Irma Caro Castelar
Cristina Muñoz Otero
Tatiana Andrea Rojas Zapata

Abstract

Background: Opsoclonus-myoclonus syndrome (OMS) is an unusual neurological and inflammatory disorder characterized by opsoclonus, myoclonus, ataxia, and behavioral changes or sleep disturbances of paraneoplastic, infectious, or idiopathic etiology. We present the case of a male infant with opsoclonus-myoclonus syndrome secondary to persistent diarrheal disease. Case report: A five-month-old patient was admitted due to involuntary jerk-type movements and apparent disconnection from the environment, with a history of persistent diarrheal disease; complementary tests were performed with no evidence of abnormality. During the stay, the sensory alteration was documented with alternation between drowsiness and irritability, skin erythema, pruritus, recurrent episodes characterized by involuntary trunk movements and extremities of the brief jerking type associated with crying and irritability with ruddiness, with subsequent episodes of head and chest hesitation. Therefore, a diagnosis of opsoclonus-myoclonus syndrome is made, triggered by a probable enteral etiology. Conclusions: The patient's unusual presentation allows a review of the literature to sensitize the health professional in the early detection and treatment of this clinical entity.

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López Vergara, P. A., Caro Castelar, I., Muñoz Otero, C., & Rojas Zapata, T. A. (2023). Opsoclonus-myoclonus syndrome associated with persistent diarrheal disease: Case report in a male infant. Pediatría, 55(Suplemento 2), 16–19. https://doi.org/10.14295/rp.v55iSuplemento2.309
Section
Case report

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