Association between sociodemographic and clinical characteristics of pregnant women with gestational syphilis and newborns with congenital syphilis, a cross-sectional study.

Main Article Content

Maria Isabel Ossa García
Sara Carolina Navarro Salgado

Abstract

Background: Congenital syphilis is considered a public health problem due to its direct impact on the population; if left undetected, it could lead to multiple complications.


Objective: Establish the relationship between the clinical and sociodemographic characteristics of mothers with gestational syphilis and the diagnosis of congenital syphilis based on a review of records from the Municipality of Armenia, Quindío, from 2016 to 2021.


Methodology: an analytical cross-sectional study was carried out that included all the records of the epidemiological surveillance database in public health of the municipality of Armenia; records that had more than 10 % missing data were discarded. The presence or absence of congenital syphilis in newborns was analyzed through bivariate analysis to establish the association of the independent versus dependent variables and, subsequently, a multivariate analysis. The qualitative variables are presented as proportions, and the quantitative variables are through central tendency and dispersion measures. The department of Quindío uses the clinical practice guideline of the Ministry of Health from 2014 for the diagnosis, approach, and treatment of gestational and congenital syphilis. In 2022, as reported in the epidemiological bulletin of week 35 by the Ministry of Health and Social Protection, the department of Quindío exceeded the national incidence in cases of congenital syphilis with an incidence rate of 3.3 per 1000 live births, the department of Quindío exceeded the national incidence in cases of congenital syphilis.


 Results: A binary logistic regression model was carried out, the variables entered into the model found that, when present in the maternal population, they explain the 28.2% probability of developing congenital syphilis.


Conclusions: according to the results of this study, there is a weak association between the sociodemographic variables of pregnant women. However, according to the diagnosis, the clinical variables may have an association, as expected.

Downloads

Download data is not yet available.

Article Details

How to Cite
Ossa García, M. I., & Navarro Salgado, S. C. (2023). Association between sociodemographic and clinical characteristics of pregnant women with gestational syphilis and newborns with congenital syphilis, a cross-sectional study. Pediatría, 56(3), e444. https://doi.org/10.14295/rp.v56i3.444
Section
Originals

References

Giraldo-Ospina B, Henao-Nieto DE, Flórez-Salazar M, Parra-Londoño F, Gómez-Giraldo EL, Mantilla-Moreno OJ. Prevalencia de sífilis en una población de gestantes de dos comunidades de un municipio de Colombia. Biosalud [Internet]. 2015; 14(2):9–18. Available from: http://dx.doi.org/10.17151/biosa.2015.14.2.2 DOI: https://doi.org/10.17151/biosa.2015.14.2.2

LaFond RE, Lukehart SA. Biological Basis for Syphilis. Clin Microbiol Rev. enero de 2006;19(1):29-49. DOI: https://doi.org/10.1128/CMR.19.1.29-49.2006

Neira Varillas MR, Donaires Toscano LF. Sífilis materna y complicaciones durante el embarazo. An Fac Med. enero de 2019;80(1):68-72. DOI: https://doi.org/10.15381/anales.v80i1.15875

Sánchez JD, https://www.facebook.com/pahowho. Pan American Health Organization / World Health Organization. 2018 [citado 9 de febrero de 2023]. OPS/OMS | Sífilis. Disponible en: https://www3.paho.org/hq/index.php?option=com_content&view=article&id=14869:sti-syphilis&Itemid=0&lang=es#gsc.tab=0

Sífilis [Internet]. Paho.org. [cited 2023 Sep 1]. Available from: https://www.paho.org/es/temas/sifilis

Garnett GP, Aral SO, Hoyle DV, Cates WJ, Anderson RM. The Natural History of Syphilis: Implications for the Transmission Dynamics and Control of Infection. Sex Transm Dis. abril de 1997;24(4):185. DOI: https://doi.org/10.1097/00007435-199704000-00002

Vigilancia, análisis, y riesgo En salud pública. Sífilis gestacional y congénita Colombia año 2020. Gov.co. Recuperado el 29 de mayo de 2023, de https://www.ins.gov.co/buscador eventos/Informesdeevento/SIF%C3%8DLIS%20GESTACIONAL%20Y%20CONG%C3%89NITA_2020.pdf

Silva MJN da, Barreto FR, Costa M da CN, Carvalho MSI de, Teixeira M da G. Congenital syphilis distribution in the State of Tocantins, Brazil, 2007-2015. Epidemiol E Serviços Saúde [Internet]. 8 de mayo de 2020 [citado 2 de marzo de 2023];29. Disponible en: http://www.scielo.br/j/ress/a/RkHVFxH3zKckxrvKHyRqKJf/?lang=en DOI: https://doi.org/10.5123/S1679-49742020000200017

Benítez J, Yépez MA, Hernández-Carrillo M, Martínez DM, Cubides-Munevar Á, Holguín-Ruiz JA, et al. Características sociodemográficas y clínicas de la sífilis gestacional en Cali, 2018. Biomédica. 15 de octubre de 2021;41(Sp. 2):140-52. DOI: https://doi.org/10.7705/biomedica.6003

de León (CLAP/PAHO) Sandra Jones (PAHO) Suzanne Serruya (CLAP/PAHO) and Ximena Pamela C. D. Bermudez (PAHO). MAGAMBMAB (brazil/moh) BG (paho) ER (paho) FP (paho) IP (paho CMBM (paho) MV (paho) MFS (clap/paho CMG (paho) MAG (paho) RM (unicef) RGP. Elimination of mother-to-child transmission of HIV and syphilis in the Americas [Internet]. Paho.org. 2016 [cited 2023 Sep 1]. Available from: https://iris.paho.org/bitstream/handle/10665.2/34072/9789275119556-eng.pdf?sequence=4&isAllowed=y

Vera SMV. Características sociodemográficas y clínicas de las gestantes con sífilis gestacional con control prenatal en los centros de salud de LA ESE ISABU del 2010 - 2017. 2010;

Caldeira JG, de Morais CC. Perfil das gestantes diagnosticadas com sífilis durante o pré-natal ou parto admitidas em maternidade de Belo Horizonte – MG.

Moraes BQS de, Correia DM, Machado MF. Desafios da sífilis congénita na atenção primária à saúde em Alagoas, Brasil, 2009-2018. Rev Univ Ind Santander Salud [Internet]. diciembre de 2022 [citado 2 de marzo de 2023];54. Disponible en: http://www.scielo.org.co/scielo.php?script=sci_abstract&pid=S0121-08072022000100324&lng=en&nrm=iso&tlng=pt DOI: https://doi.org/10.18273/saluduis.54.e:22031

Almeida AS de, Andrade J, Fermiano R, Jamas MT, Carvalhaes MA de BL, Parada CMG de L. Syphilis in pregnancy, factors associated with congenital syphilis and newborn conditions at birth. Texto Contexto - Enferm [Internet]. 16 de agosto de 2021 [citado 8 de febrero de 2023];30. Disponible en: http://www.scielo.br/j/tce/a/DcJG3jTsbHtr8BvRT3PLZsm/?lang=en DOI: https://doi.org/10.1590/1980-265x-tce-2020-0423

Paula MA de, Simões LA, Mendes JC, Vieira EW, Matozinhos FP, Silva TMR da. Diagnóstico e tratamento da sífilis em gestantes nos serviços de Atenção Básica. Ciênc Saúde Coletiva. 22 de julio de 2022;27:3331-40. DOI: https://doi.org/10.1590/1413-81232022278.05022022

Sánchez EFZ, Escobar ECH, González CRL, Mora PAV. Análisis de técnicas treponémicas y no treponémicas en el tamizaje serológico de sífilis. Rev Cuba Hematol Inmunol Hemoter [Internet]. 1 de agosto de 2017 [citado 8 de febrero de 2023];33(3). Disponible en: https://revhematologia.sld.cu/index.php/hih/article/view/593

García-Legaz Martínez M, Hernández-Bel P, Magdaleno-Tapial J, Martínez-Doménech A, Navalpotro D, Alegre-de Miquel V, et al. Utilidad de las nuevas pruebas treponémicas automatizadas en el diagnóstico de la sífilis precoz. A propósito de 15 casos. Actas Dermo-Sifiliogr Ed Impr. 2020;135-42. DOI: https://doi.org/10.1016/j.ad.2019.01.013

Reis AR de P, Duarte G, Menegueti MG, Reis RK, Silva ACR e, Gir E. Reactive treponemal and non-treponemal tests in pregnant women and associated factors. Rev Esc Enferm USP [Internet]. 25 de noviembre de 2022 [citado 5 de marzo de 2023];56. Disponible en: http://www.scielo.br/j/reeusp/a/QxvqkqjHK68GN8nstV55G7j/?lang=en DOI: https://doi.org/10.1590/1980-220x-reeusp-2022-0146pt

Gliddon HD, Peeling RW, Kamb ML, Toskin I, Wi TE, Taylor MM. A systematic review and meta-analysis of studies evaluating the performance and operational characteristics of dual point-of-care tests for HIV and syphilis. Sex Transm Infect. 1 de diciembre de 2017;93(S4):S3-15. DOI: https://doi.org/10.1136/sextrans-2016-053069

Rowe CR, Newberry DM, Jnah AJ. Congenital Syphilis: A Discussion of Epidemiology, Diagnosis, Management, and Nurses' Role in Early Identification and Treatment. Adv Neonatal Care. 2018 Dec;18(6):438-445. doi: 10.1097/ANC.0000000000000534. PMID: 30020089. DOI: https://doi.org/10.1097/ANC.0000000000000534

Nakku-Joloba E, Kiguli J, Kayemba CN, Twimukye A, Mbazira JK, Parkes-Ratanshi R, Birungi M, Kyenkya J, Byamugisha J, Gaydos C, Manabe YC. Perspectives on male partner notification and treatment for syphilis among antenatal women and their partners in Kampala and Wakiso districts, Uganda. BMC Infect Dis. 2019 Feb 6;19(1):124. doi: 10.1186/s12879-019-3695-y. PMID: 30727950; PMCID: PMC6366113. DOI: https://doi.org/10.1186/s12879-019-3695-y

Garcés JP, Rubiano LC, Orobio Y, Castaño M, Benavides E, Cruz A, et al. La educación del personal de salud: clave para la eliminación de la sífilis congénita en Colombia. Biomédica. septiembre de 2017;37(3):416-24. DOI: https://doi.org/10.7705/biomedica.v37i3.3397

Frenk J, Chen L, Bhutta ZA, Cohen J, Crisp N, Evans T, et al. Health professionals for a new century: transforming education to strengthen health systems in an interdependent world. The Lancet. 4 de diciembre de 2010;376(9756):1923-58. DOI: https://doi.org/10.1016/S0140-6736(10)61854-5

Garcia PJ, Cotrina A, Gotuzzo E, González E, Buffardi AL. Research training needs in Peruvian national TB/HIV programs. BMC Med Educ. 28 de septiembre de 2010;10(1):63. DOI: https://doi.org/10.1186/1472-6920-10-63

de Sáenz Adriana Cruz Aconcha Liliana Gallego Vélez Hugo Enrique López Ramos Hoover Canaval Erazo María Teresa Ochoa Manjarrés Vivian Marcela Molano Soto HGGDLCCCZPCMRBCCMJPAGCHHDPRTEÁMSEMMYC. Guía de práctica clínica (GPC) basada en la evidencia para la atención integral de la sífilis gestacional y congénita [Internet]. Gov.co. 2014 [cited 2023 Sep 1]. Available from: https://www.minsalud.gov.co/sites/rid/Lists/BibliotecaDigital/RIDE/INEC/IETS/gpc-guia-corta-sifilis.pdf

Pérez ATO. Sífilis y embarazo. Mem Curso Actual En Ginecol Obstet. 2019;185-94.

Similar Articles

<< < 8 9 10 11 12 13 14 15 16 17 > >> 

You may also start an advanced similarity search for this article.