Dermatological emergency in pediatrics, DRESS syndrome

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Ivan David De La Peña Sanabria
Nataly Chavarriaga
Jose Ángel Pineda Marriaga

Abstract

Skin reactions induced by drugs in pediatrics are rare entities; However, these are associated with great morbidity and mortality. The DRESS syndrome or drug reaction with eosinophilia and systemic involvement is one of the most representative but little diagnosed due to its low frequency.


Case summary: female minor infant was admitted for postseptal cellulitis which requires vancomycin management, who had clinical deterioration, fever and maculopapular rash with erythematous disseminated background, unmodulated shock, edema, elevation of aminotrasferasas, prolonged clotting times and hypoalbuminemia; Eosinophilia of 8400 and impaired hepatic function, which completed clinical criteria for Dress syndrome. The evolution of the patient was satisfactory, without relapse of rash or fever, she was managed with skin support and hydration treatment, with satisfactory resolution and evolution.
Conclusions: The diagnosis of Dress, despite being exclusionary, should be considered in all children with prior exposure to high-risk medications, may be associated with complications in the acute stage, and despite a good long-term prognosis, it can be associated with complications such as autoimmune diseases, chronic renal or hepatic involvement which should be evaluated as part of ambulatory followup by the pediatrician.

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How to Cite
De La Peña Sanabria, I. D., Chavarriaga, N., & Pineda Marriaga, J. Ángel. (2018). Dermatological emergency in pediatrics, DRESS syndrome. Pediatría, 51(1), 19–23. https://doi.org/10.14295/pediatr.v51i1.100
Section
Case report

References

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