Coronavirus disease 2019 (COVID-19) in children and adolescents: a multicenter study

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Fredy Orlando Mendivelso Duarte
Jairo Enrique Moreno Gómez
Deisy Johana González González
Martha Liliana Mosquera Martínez
Humberto Rivera Martínez
Milena Rodríguez Bedoya

Abstract

Background: The first case of the 2019 new coronavirus disease (COVID-19) was confirmed on March 6, 2020. There are already more than 2,2 million infected in Colombia. COVID-19 testing in children is still limited. Objective: Identify clinical and epidemiological characteristics and transmission patterns of pediatric patients with COVID-19 in Colombia. Methods:  Prospective cohort study with 4 469 patients aged 0-17 years who consulted for signs and symptoms compatible with SARS-CoV-2 infection in the emergency room of eight institutions in three cities of Colombia. The cases were confirmed by RT-PCR or positive antigen test. The epidemic curves were constructed by the date of diagnosis. Descriptive statistics and non-parametric tests were used to analyze clinical characteristics, pathological history, epidemiological risk, and relevant outcomes. p <0.05 were considered statistically significant Results: A total of 602 (13.5 %) laboratory-confirmed cases were identified and, compared to the general population, represented 5.1 % of the cases. The median age of all patients was 3 years (interquartile range: 1-9 years) and the time of evolution until diagnosis was 2 days (range: 1 to 3 days). The highest incidence of cases occurred in July and December. 15.61 % of the confirmed children had pre-existing diseases and the mortality rate in the cohort was 0.3 %. Conclusions: Children of any age are susceptible to COVID-19, but in general, its evolution is milder than in adults, and deaths were rare.


 

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Mendivelso Duarte, F. O., Moreno Gómez, J. E., González González, D. J. ., Mosquera Martínez , M. L., Rivera Martínez, H., & Rodríguez Bedoya, M. (2021). Coronavirus disease 2019 (COVID-19) in children and adolescents: a multicenter study. Pediatría, 54(3), 95–104. https://doi.org/10.14295/rp.v54i3.288
Section
Originals
Author Biography

Fredy Orlando Mendivelso Duarte, MD. Cirujano. Epidemiólogo Clínico. MPH. MSc. FETP. Clínica Reina Sofía, Departamento de Pediatría. Grupo de Investigación en Epidemiología Aplicada, Instituto Nacional de Salud, Bogotá D. C.

  1. MD. Cirujano. Epidemiólogo Clínico. MPH. MSc. FETP. Clínica Reina Sofía, Departamento de Pediatría. Grupo de Investigación en Epidemiología Aplicada, Instituto Nacional de Salud, Bogotá D. C.

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