Urinary tract infection in pediatric population with urological abnormalities in a fourth level hospital in Bogota, Colombia
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Abstract
Introduction: Urological anomalies represent one-third of congenital malformations worldwide and increase pediatric patients' risk of urinary tract infections (UTIs). The literature on this population's resistance patterns of microorganisms involved in UTIs is scarce. It is unknown if it leads to a different empirical treatment than in patients without alterations. Methods: The objective of the study was to characterize the pediatric population with urological malformations and UTIs in a fourth-level institution and to determine which were the most frequent etiological microorganisms and their patterns of bacterial resistance. A cross-sectional study was developed in patients younger than ten diagnosed with UTI and urological abnormality who assisted to the hospital between January 2014 and December 2019. The data was recorded in the REDCap application and processed in Excel®. Results: 145 children with urological malformations consulted the hospital and were diagnosed with UTIs during the study period. A higher prevalence was found in girls, the average age of UTIs presentation was 23 months. The most frequent anomalies were kidney malformations, and the most frequent microorganism was Escherichia coli, followed by Klebsiella pneumoniae and Proteus mirabilis. The most frequent resistance pattern of Escherichia coli was penicillinase producer. Conclusions: It is essential to periodically characterize urinary tract infections in pediatric patients with urological abnormalities to have updated data to guide treatment and guidelines, thus providing better medical care, preventing complications, and resulting in a better quality of life for these patients.
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